Endocrine Abstracts

IntroductionJacobsen syndrome (JS) is a rare gene disorder caused by a terminal deletion of the long arm of chromosome 11. The estimated prevalence of Jacobsen syndrome is 1/100.000 births. It is most commonly presented with psychomotor and physical growth retardation, dysmorphic facial features, thrombocytopenia or pancytopenia. It is also characterized by congenital heart defects, and kidney, gastrointestinal tract, genitalia, CNS and skeletal deformit...

IntroductionGraves’ disease (GD) is an autoimmune thyroiditis frequently associated with development of Graves’ orbitopathy (GO). Diplopia (double vision) is a major determinant of work disability in patients with GO. The aim of our study was to assess the prevalence of diplopia and strabismus in patients with GO.MethodsThis is a single-center observational study in an outpatient clinic of autoimmun...

Background: Bariatric surgery (BS) is a well-documented treatment targeting weight loss excess. There is little evidence of the impact of BS on antenatal glycaemic control. We present three cases of pregnancy post-BS, who experienced various degrees of hypoglycaemia during gestation.Case presentations: Three women aged 25-, 26-, and 36-years-old, who were previously euglycaemic, presented to the joint antenatal clinic wi...

Background: Bariatric surgery (BS) is a well-documented treatment targeting weight loss excess. There is little evidence on the impact of BS on antenatal glycaemic control. We present four cases of pregnancy post-BS, reviewed in the joint antenatal clinic, who experienced various degrees of hypoglycaemia during pregnancy.Case presentations: Four pregnant women (cases A–D, aged 25–36-years-old, 3–8years pos...

Graves’ orbitopathy (GO) development or reactivation is a well-recognised complication of radioactive iodine (RAI), with possible lower incidence in a recent series. We performed a retrospective audit of Graves’ disease patients treated with RAI at our centre over a 5-year period. We recorded the GO incidence after RAI treatment, risk factors present, and steroid prophylaxis use. Data collected: smoking status, thyroid-stimulating hormone receptor antibody (TRAb), GO...

Introduction/Aim: In this study, we aimed to evaluate the long-term impact of the diabetes awareness day in Greece (in 2016-2023), which is organized every year in November, by examining the relevant local internet searches.Materials/Methods: We collected monthly data with Google Trends, exclusively from Greece, on relevant [online] search volumes (RSVs), with keywords "diabetes" (study group; in medical/scientific and lay terms, in Greek and in ...

Introduction: Sleep disorders, including insomnia disorder, can affect all aspects of personal life and often occur during perimenopause, menopause, and postmenopause. Data on the number of women who suffer from sleep disorders during menopause range from 28% to 63%. Cognitive behavioral therapy for insomnia (CBT-I) is a multi-component, drug-free treatment approach that targets behavioral and cognitive factors that contribute to chronic sleep disorders. The aim of this scope ...

Euthyroid sick syndrome also known as nonthyroidal illness syndrome is the reaction of the thyroid gland to severe disease. The SARS-CoV-2 virus affects the thyroid gland and may cause subacute thyroiditis, autoimmune Hashimoto’s thyroiditis, Graves’ disease, exacerbation of Graves’ disease and a form of silent thyroiditis. The aim was to study thyroid hormone levels and identify the presence of euthyroid sick syndrome in the context of severe SARS-CoV-2 disease...

Introduction: Current guidelines emphasize the important role of Continuous Glucose Monitoring (CGM) for type 1 diabetes mellitus (T1DM) management. The aim of the GlucoseML study is the development of a mobile health system for T1DM self-management based on CGM data, physical activity, food intake and insulin dosage. We herein present the development and evaluation of a univariate Autoregressive Moving Average (ARMA) prediction model of interstitial glucose concentration for ...

Summary: 59-year-old female diagnosed at the age of 41 in 2004 with pseudohypoparathyroidism (PHP) initially presenting with raised PTH 152 pmol/l (1.6-6.9), Phosphate 1.91 mmol/l (0.87-1.45), adjusted calcium 1.90 mmol/l (2.20-2.60), raised ALP 600 units/l (0-129) and low vitamin D 29 nmol/l. Since diagnosis started on alfacalcidol 1 mg daily and Calcichew-D3. Investigations by hepatology team in the view of persistently raised ALP showed normal liver ultrasound, Fibroscan an...